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The approval builds on Uzedys 2023 indication for schizophrenia and data from Phase 3 RISE and SHINE trials confirming efficacy and tolerability
A 2024 safety review in ScienceDirect noted that tirzepatide may have slightly better GI tolerability than semaglutide, likely because of its dual mechanism ( ScienceDirect , 2024)
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The body produces glutathione naturally, but our levels are not fixed
Around 9% of people experience diarrhea while on Ozempic, according to controlled trials in people with Type 2 diabetes
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