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Ahrn B, Hirsch IB, Pieber TR et al (2016) Efficacy and safety of liraglutide added to capped insulin treatment in subjects with type 1 diabetes: the ADJUNCT TWO randomized trial

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These effects collectively improve postprandial glucose excursions and reduce fasting blood glucose levels in patients with type 2 diabetes

Therefore, the two crucial mechanisms are that the transduction of PAR polymer to mitochondrial and the transfer of AIF from mitochondrial to nucleus to degrade chromatin

High-throughput proteomics: a methodological mini-review