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Novo Nordisk's patent for Saxenda expires later this year, and rivals Teva, Pfizer and Mylan are all expected to launch generic versions of liraglutide later in 2024

Phase 2 data in type 2 diabetes showed CagriSema reduced HbA1c by 2.2 percentage points compared to 1.8 with semaglutide alone and 0.9 with cagrilintide alone, while achieving 15.6% weight loss versus 5.1% with semaglutide alone

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This slowing effect occurs through several mechanisms: GLP-1 reduces gastric motility, decreases the force of stomach contractions, and influences the pyloric sphincter (the valve between the stomach and small intestine)