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Participants were assigned to receive weekly doses of retatrutide at 1 mg, 4 mg, 8 mg, or 12 mg for 48 weeks, or placebo
GLP-1 users whove seen improvements while taking this medication face a stark choice: Pay sometimes-exorbitant costs to continue the medication outside of their prescription plan or risk the progress theyve made and their overall health
The potential downsides of GLP-1 medications No drug is without side effects, and for GLP-1 medications, these might be: Gastrointestinal issues such as constipation or diarrhea General nausea and vomiting, or nausea caused by certain smells Pain or tenderness in the stomach or abdominal area And more serious side effects including hypoglycemia, pancreatitis, and gallstones The other concern many have with GLP-1 medications is how long a patient must be on them to sustain their weight loss
That means it is designed to act on three metabolic hormone pathways: Most people are already familiar with GLP-1 medications because of drugs like Ozempic, Wegovy, Mounjaro, and Zepbound
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