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More recent multi-society guidance has shifted toward individualized risk assessment, and many patients may be able to continue GLP-1 medications before surgery when their anesthesia team determines it is safe
oral regimens), and trial endpoints better tuned to metabolic mechanisms
MOTS-c acts on mitochondrial signalling
However, to date, the number of heart failure events identified in clinical studies with linagliptin has been small, and reported in studies that were not specifically designed to assess cardiac failure
This phase is about tolerance, not results
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