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Los estudios LEAD investigaron la eficacia de liraglutida (1,80mg diario) en DM2, presentando una perdida ponderal promedio en los estudios de 2,10 a 3,30%18
hazard ratio, 0.76
230 adults who are obese or overweight (average BMI ~39.5) were randomly assigned to take a placebo, or aleniglipron at one of three doses (45mg, 90mg, or 120mg) for 36 weeks, with the dose gradually increasing over time
The clinical proof of concept comes from CagriSema, the combination of cagrilintide with semaglutide
Community planning typically uses 4-8 week cycles to allow time for skin or hair changes to become visible
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