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When these proteins are abnormally expressed, the overload cytosolic free ferrous iron leads to intracellular ROS accumulation via the Fenton reaction, which eventually promotes lipid peroxides formation and ferroptosis occurrence (186)
The distribution of the bases within the transcripts was determined using GATKs CollectRnaSeqMetrics
Does Not Contain
is supported by the National Key R&D Program of China (2022YFA1303000), the National Natural Science Foundation of China (32225025, 32321004, 92254305), the CAS Project for Young Scientists in Basic Research (YSBR-076) and the New Cornerstone Science Foundation through the XPLORER PRIZE
Brain, Behavior, & Immunity Health 5: 100089
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