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10.1523/JNEUROSCI.2855-11.2011 199 MelkeJ.Goubran BotrosH.ChasteP.BetancurC.NygrenG.AnckarsterH.et al

Moschandrea et al

Essentially, MOTS-c helps orchestrate a genome-wide response that mimics some benefits of exercise at the cellular level, a phenomenon sometimes called mitohormesis (where a mild stress like exercise leads to stronger cellular function)