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In the clinical setting, prolonged azole exposure in patients undergoing antifungal therapy may lead to the selection of resistant strains that persist despite treatment and continue to cause infection (Howard et al., 2009)
These risks include gastrointestinal disorders, low blood pressure, nephrolithiasis (kidney stone disease), interstitial nephritis, and drug-induced pancreatitis
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Whilst routine pancreatic enzyme testing is not indicated in asymptomatic patients, clinicians should maintain a low threshold for investigation if symptoms develop
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Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone
