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Specifically, ferroptosis is defined as an iron-dependent regulated form of necrosis that is caused by massive lipid peroxidation-mediated membrane damage, and this regulated necrosis plays a crucial role in the development and disease of various organisms [12, 13]

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The same research showed berberine produced only slight reductions in body mass index (about 0.5 points) and waist size (less than half an inch)