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This is particularly important in the current context where the daily assessment of pain and bleeding represents numerous options for understanding patient experiences of symptoms over time (e.g., average pain over observation period, worst pain over observation period, pain on bleeding days, pain on non-bleeding days) as well as change in these symptoms over time (absolute change in symptom severity scores vs relative change in symptom severity scores)

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Interestingly, RSL3 did not suppress p70S6K protein levels in HThF cells to the extent observed in K1 cells (Fig

Overall, the existing body of evidence remains exploratory and limited in scope