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Using a PCPA-induced insomnia mouse model, researchers assessed its impact on neurotransmitters like 5-HT, glutamate, dopamine, and melatonin
The central mechanism involves both homeostatic (energy balance) and hedonic (food reward) pathways, providing comprehensive appetite regulation
BioMed Res Int 2015:648108
Animal Model Evidence The systemic evidence base is entirely preclinical: Pulmonary fibrosis (mouse model): Intraperitoneal GHK-Cu at 0.2-20 micrograms/g/day protected against bleomycin-induced lung fibrosis by inhibiting TGF-beta1/Smad signaling and reducing oxidative stress (PMID 31809714)
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Its strong antioxidant properties shield skin cells from oxidative stress, which can worsen inflammation, by helping neutralise free radicals
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