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Most retatrutide-related diarrhea is mild to moderate, peaks during dose escalation, and resolves within 8 to 12 weeks for the majority of participants

These mechanisms support the clinical development of glucagon like peptide-1 receptor agonist (GLP-1RA) in the treatment of obesity

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This is one of the most important things to understand about contrave medication for weight loss: its a long-term commitment, not a short course

Nausea (common and usually mild) Nausea is reported more often in the first few days after each new dose