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Gender-Differentiated AE Signals For the overall AEs with available gender data, females still constituted the majority at the SOC level, with 78.5% for injury, poisoning and procedural complications (n = 36,152), 80.5% for general disorders and administration site conditions (n = 31240) and 73.3% for gastrointestinal disorders (n = 21,770) (Figure 2A)