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J Clin Invest 2017;127:383544.ArticlePubMedPMC 58
Together, these biological effects help mitigate hallmarks of aging such as sarcopenia, metabolic inflexibility, inflammatory vulnerability, and impaired exercise tolerance ( Figure 2 )
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To rule out CC, molecular screening on PRKAR1A gene was performed using Sanger sequencing, and no germline pathogenic variant in PRKAR1A was identified
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