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Hematocrit and reticulocyte counts should be repeated daily from the fifth to seventh days of therapy and then frequently until the hematocrit is normal
Recommendation Use for 46 weeks Then take a 24 week break This break allows NNMT levels to rebound and resensitizes the body to the peptides metabolic signaling
It was designed to confirm the Phase 2b results and advance AOD 9604 toward regulatory approval
Phase 2 trials used subcutaneous 1 mg/day
Cell studies Show that 5-Amino-1MQ can block NNMT and change related metabolites in controlled lab conditions
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