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The pill is not yet available on the NHS : NHS access depends on a separate NICE technology appraisal, which is not expected to conclude in 2026
Clinicians soon noticed that many patients experienced substantial weight loss, often without intentional dietary changes
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In clinical trials, the dual GIP and GLP-1 receptor agonist tirzepatide has been shown to result in substantial weight reduction (~20%) in people with obesity, with and without type 2 diabetes 2,3
Others prefer taking the medication on an empty stomach for maximum absorption
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