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Docosahexaenoic acid (DHA) and EPA were shown to reverse elevated TNF- levels and ameliorate anxious behaviors (117)

doi: 10.3390/pharmaceutics17010119

The effects become visible within four weeks, and the significant effects may need a maximum of three months

Future work will use longitudinal profiling and single-cell sequencing to assess cell-type-specific GSH roles 5 Conclusion In conclusion, by leveraging multi-omics integration, the present study identified GSH metabolism as a pivotal node in SAE, while providing a comprehensive molecular framework for SAE pathogenesis, and linking microglia-driven neuroinflammation to hippocampal oxidative damage

Nat Commun 15 , 1733 (2024)