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These factors can change the needed dosage

Angiogenesis via VEGF and FGF-2: At concentrations as low as 1 nM, GHK-Cu increases expression of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in irradiated human dermal fibroblasts, accelerating capillary formation in damaged tissue

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By shifting the focus from suppressing the immune system to actively healing the gut barrier, you change the entire biological landscape of your body