Several meta-analyses suggest a reduced incidence of gestational diabetes with this dosing strategy, but authors emphasize that evidence quality is moderate and that further large-scale randomized trials are needed before universal recommendations can be made.9 24 25 26 Psychiatric research (high-dose, limited evidence) Studies exploring inositol for panic disorder, obsessive-compulsive disorder, or depression have used much higher doses often 12,00018,000mg per day.35 36 37 While some small trials reported symptom improvement, results have been inconsistent, and these doses are far higher than those used for metabolic or reproductive purposes.38 Most reviews do not recommend high-dose inositol for mental health outside of clinical supervision.42 Across contexts, higher doses do not consistently produce stronger effects
SOURCES: VCU Stravitz-Sanyal Institute for Liver Disease and Metabolic Health, news release, April 30, 2025
This is because NAD+ therapy stimulates cellular repair, which can briefly increase the release of metabolic waste
Miccheli, F
Heally notes, Most side effects seen in clinical use are mild and temporary. By understanding these possible impacts, including potential changes in sleep patterns like vivid dreams or short-term insomnia, you can feel more equipped and supported throughout your journey with this treatment
