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People who should not take semaglutide include: Those with a personal or family history of MTC or MEN 2 Those with active pancreatitis People with serious gastrointestinal disease that affects digestion Pregnant or breastfeeding women should also avoid semaglutide, as it has not been studied enough in these groups
Dig Dis Sci 1987
Semaglutide should be discontinued at least 2 months before planned pregnancy, whilst topiramate is now contraindicated for migraine prophylaxis in women of childbearing potential unless a Pregnancy Prevention Programme is followed with highly effective contraception
Patients with recurrent depression exhibit reduced hippocampal volume and hippocampal atrophy in the brain when compared to healthy controls ( Figure 2 ) (Sheline et al., 1999)
Local industry capacity is rising, reducing dependency on imports and bolstering national expertise
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