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AHAs (General): Include other acids such as lactic acid, citric acid, and mandelic acid
Novel economic incentives and policies must be enacted to revitalize depleted antibiotic product development and prioritize using essential drugs for the most critical resistant pathogens [28]
In summary, GSH enables antibiotic inactivation by serving as a substrate for detoxifying enzymes, such as FosA, and by modulating the expression or stability of antibiotic-degrading enzymes, including the downregulation of NDM-1
Due to its shorter sequence, TB-500 offers enhanced metabolic stability and amenability to synthetic optimization compared to the parent protein
Thiele, J.J., Weber, S.U
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