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when chronically elevated, it promotes resorption
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NNMT consumes S-adenosylmethionine (SAM) as a methyl donor, so inhibiting NNMT could theoretically increase SAM availability for other methylation reactions
Eli Lillys stock price has climbed more than 50% since the FDA approved Zepbound in November 2023, pushing its market cap above $800 billion
The highest caution is usually needed in patients who already have moderate to severe retinopathy , diabetic macular edema, or recent unstable retinal disease
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