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Is Cagrilintide Peptide approved or intended for human use
and M.Z.) and the Innovative Research Team of High-Level Local Universities in Shanghai (to M.Z.)
Kim G, Bae J-H
Efficacy: Semaglutide has superior reductions in HbA1c and body weight compared to other agents, while tirzepatide, a dual GLP-1/GIP receptor agonist, shows even greater efficacy but with higher rates of adverse events
Another obstacle in developing drugs targeting metabolism is that drugs may fail to reproduce the beneficial effect seen in preclinical models, and thus, be screened out in early clinical trials (232, 233)
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