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This makes it one of the rare actives that works on three pathways at once: This makes it effective for treating melasma, post-inflammatory hyperpigmentation (PIH), and sun-induced dark spots

Annals of Allergy, Asthma & Immunology, 131(2), 250-255

doi: 10.1371/journal.pone.0110886 84 DuffieldAJThomsonCD

Homocysteine levels may also look normal on testing, cloaking genuine issues with methylation (a 'false negative')

Revive If you are feeling tired and run down all the time, suffering from unexplained aches and pains and continually falling victim to colds and other infections, then you may have a vitamin B12 deficiency