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The Graves disease antibody, known as thyrotropin receptor antibody (TRAb), mimics the regulatory actions of the pituitary hormone, hijacking normal control of the thyroid
N Engl J Med 328:11571162
For ketamine/xylazine condition, all mice were initially anesthetized with 5% isoflurane in oxygen and air and then given an induction dose with a mixture of ketamine (100 mg/kg) and xylazine (10 mg/kg) intraperitoneally 107,109
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