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Expert opinion on drug metabolism & toxicology 5 , 12231244, doi: 10.1517/17425250903143769 (2009)

Additionally, some substances can be eliminated through sweat

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Mechanistically, it works upstream of structural damage by blocking NF-kappaB before the downstream cytokine cascade (TNF-alpha, IL-1beta, IL-6) gets going, rather than mopping up inflammation after the fact