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1996 Axelsson, L
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Still, research shows that GLP-1 drugs can produce the most significant weight loss
While the gastrointestinal side effects of GLP-1s are very common and manageable for many, between 15% and 25% of people simply can't tolerate them
"People can lose more fat." Retatrutide: Next-gen obesity drug helps patients lose 28% of body weight In a phase-three trial by Eli Lilly, patients on the highest dose lost an average of 28.3% of their body weight over a year and a half, and more than 45% of participants lost at least 30%, a level of efficacy the company said approaches results seen with bariatric surgery
As a result, the binding of both GLP-1 and GIP makes it possible to more effectively use insulin and better manage blood sugar levels after a meal
