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Do Semaglutide GLP-1 shots work for chronic weight loss
One of the concerns is whether Semaglutide can cause or worsen Gastroesophageal Reflux Disease (GERD)
How to Break a Weight Loss Plateau on Mounjaro Adjust calorie intake slightly Increase workout intensity or variation Reassess daily habits Stay consistent over time If you feel mounjaro treatment stopped working, it is often a plateau rather than failure
Some may start with even lower doses if compounded formulations are available
Based on the current stage of clinical development and estimated trial completion dates registered on ClinicalTrials.gov, a realistic earliest possible timeline might be considered as follows: 20252026: Completion of key phase 3 TRIUMPH trial data 20262027: Potential regulatory submission to the MHRA (and FDA/EMA in parallel) 20272028: Possible MHRA marketing authorisation, subject to satisfactory review 2028 onwards: NICE technology appraisal and potential NHS commissioning decision These timelines are speculative and depend on multiple variables, including trial outcomes, the completeness of the regulatory submission, MHRA review timelines, and NICE deliberations
