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doi:10.3109/03009749709105320
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Favored by longevity-focused researchers investigating systemic tissue support , soft tissue remodeling , and skin quality from the inside out
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& Pedersen, L
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These data suggest that ferroptosis plays a critical role in renal fibrosis by sustaining the activation of TGF-/Smad signaling and promoting the release of downstream profibrotic factors, ultimately contributing to fibrogenesis
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Surplus ROS attack DNA, inducing damage [107], and oxidize proteins, leading to protein misfolding and functional loss [108]
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