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Skin concerns: Dark spots, post-acne marks, uneven tone, dullness, and loss of elasticity
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Sharp pain in the lower left abdomen in females can become a critical warning sign, especially when it occurs suddenly, is severe, or is accompanied by symptoms such as fever, persistent vomiting, or fainting
Lactic acidosis reports were markedly lower with combination therapy (567 vs 15,789), as were acute kidney injury (675 vs 7,694), diarrhoea (3,890 vs 6,922), and metabolic acidosis (203 vs 4,713), suggesting that the addition of GLP-1 RAs to metformin may mitigate serious adverse effects associated with metformin alone (Table 2)
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