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FDA is concerned that identifying your firm and not the actual manufacturers may have been an attempt to circumvent safeguards associated with [the import alert] and may pose a risk to consumers of receiving substandard GLP-1 APIs, the agency said
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Additionally, vomiting or diarrhoea can lead to electrolyte imbalances and dehydration, both of which influence energy levels
The STEP (Semaglutide Treatment Effect in People with Obesity) clinical trial programme demonstrated that adults using semaglutide 2.4 mg weekly alongside lifestyle intervention lost an average of approximately 15% of their body weight over 68 weeks, compared to around 2.4% with placebo. NICE approved Wegovy for use in specialist weight management services in the UK in 2023 (TA875), recognising its clinical effectiveness. Ongoing research continues to explore its cardiovascular benefits, with the SELECT trial showing a significant reduction in major cardiovascular events in people with obesity
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