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We previously showed the presence of mitochondrial dysfunction as early as P15 in the motor cortex, but more precisely in the CSMN of TDP-43 A315T mice 17 , one of the best characterized mouse models of TDP-43 pathology 16,19,33,34
11 :e0154206
Phase 2 Published 2023 The New England Journal of Medicine The most-cited medical journal in the world Jastreboff et al., 2023 338 adults with obesity, randomized to placebo or one of four Retatrutide doses (1, 4, 8, 12 mg weekly)
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Virmani and Cirulli, 2022
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