Adverse Reactions/Side Effects Mild transient diarrhea, polycythemia vera, peripheral vascular thrombosis, itching transitory exanthema, feeling of swelling of entire body, anaphylactic shock and death
Planchard D, Janne PA, Cheng Y, Yang JC, Yanagitani N, Kim SW, et al
Among these diseases, the potential common denominators in the pathologic mechanisms are processes such as cell proliferation and differentiation, inflammation, and fibrosis, and the role of Wnt/-catenin signalling in these processes is well established, explaining why the Wnt/-catenin signalling pathway plays a key regulatory role in these diseases
Gene therapy offers an alternative avenue
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