810 CsA@ApoFn reduces the content of unstable iron pool and lipid peroxide by increasing the expression of GPX4 protein, thereby inhibiting ferroptosis in ischemic cardiomyocytes, 810 providing a promising strategy for the treatment of myocardial I/R injury
Participating in glutathione binding reactions as a transferase, GST is widely dispersed across the cytoplasm of various cell types, acting as a critical component in the metabolism of numerous intrinsic and extrinsic toxins
Bayesian models forecast that although prevalence may plateau or modestly decline by 2040, mortality and overall disease burden will continue to rise, driven largely by population aging, especially in high-income countries [1] and increased environmental toxic compounds
It has been reported that GSH is reduced by the following side reactions under neutral conditions (Methods in Enzymology, 1985, 113, 548)
DNA was purified using phenol-chloroform-isoamyl alcohol extraction and ethanol precipitation