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Retatrutide side effects and tolerability Reported side effects in research settings have most commonly involved the gastrointestinal system
Additionally, exendin-4 treatment mitigated high glucose-induced mitochondrial dysfunction, as evidenced by reduced expression levels of mitochondrial function-associated genes mitochondrial calcium uniporter (MCU) and uncoupling protein 3 (UCP3), as well as the mitochondrial fission-related gene dynamin-related protein 1 (DRP1) [79]
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Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis
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