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We utilize High-Performance Liquid Chromatography (HPLC) coupled with Mass Spectrometry (MS) to confirm an absolute chemical purity profile of 99% or greater for the active small molecule matrix before encapsulation

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Because GCLC floxed X Iba1-Cre mice died early (around 34 months of age) due to developmental defects, we could not assess the effect of microglial GCLC-deficiency on brain atrophy

While these agents are not yet formally approved for IIH, their potential dual benefit of weight loss and ICP reduction could substantially enhance the current management of IIH