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These hemodynamic interactions are not reflected in current prescribing information for tirzepatide, not because they have been evaluated and found absent, but because patients with hEDS and POTS were not systematically enrolled in the pivotal SURMOUNT trials, which excluded individuals with significant cardiovascular, renal, and neurological comorbidities

Any inconsistency between public claims and investigational status may be interpreted as evidence of consumer deception or misbranding

P., Lopes, R

200 Genomic amplifications of DDR genes also contribute to broad-spectrum resistance