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PACE for 72 h on PC_SS1 evolved several mutations conserved among PACE clones: Thr167Ala, Pro174Leu and Ser240Asn (Supplementary Table 1)
However, the pivotal 36-week Phase 2 trial showed a larger range of mean loss, from 9.4% to 14.7%, across doses, confirming robust dose-dependent effects
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N Engl J Med 387(3):205216
Eating less sugar and starchy food, and prioritizing protein and healthy fats at your meals, is one simple way to start balancing blood sugar
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