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Key Takeaways Hydroquinone denatures tyrosinase by covalently binding to the enzyme's copper active site, halting melanin synthesis within 46 weeks of daily topical application
As a tripeptide composed of glutamate, cysteine, and glycine, it functions as the primary thiol-based redox buffer, neutralizing reactive oxygen species (ROS), supporting Phase II detoxification pathways, and facilitating the excretion of xenobiotics and heavy metals [1] [8]
HEK-293T were from American Type Culture Collection (ATCC), and cultured in Dulbeccos modified Eagles medium (DMEM) (Cytiva, SH30003.02) supplemented with 10% fetal bovine serum (FBS, Cytiva)
Findings from preclinical research suggest maqui berry extract may decrease glucose production in the liver and increase insulin sensitivity (Rojo 2012)
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