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Effects of early adolescent environmental enrichment on cognitive dysfunction, prefrontal cortex development, and inflammatory cytokines after early life stress
Georgieff MK
In ALS models, SOD1 mutations do not markedly alter astrocytic baseline states but lower the threshold for reactivity, which sensitizes astrocytes to oxidative, glutamatergic and inflammatory stress and drives exaggerated reactive responses to otherwise moderate insults 80
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SRIF-positive neurons have also been described downstream in the olfactory pathway
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