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Subpopulations may survive high drug concentrations through stress response pathways, while dormant phenotypes persist within host niches like macrophages ( Candida auris and Rhodosporidiobolus fluvialis , underscores the urgency for new therapeutic approaches (Jackson et al., 2019

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The most strongly downregulated transcripts related to detoxification in viruliferous BLHs were glycine N-acetyltransferase-like protein 3 and UDP-glucosyltransferase 2-like, with -10.28 and -5.10-fold downregulation, respectively

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Particularly, NASH and CKD are areas where successful drug development has been challenging, and a new effective treatment could be a significant revenue driver