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The SURMOUNT-4 trial assessed the weight maintenance with tirzepatide and had also two periods: a 36-week open-label lead-in period during which all participants took tirzepatide, followed by a 52-week double-blind treatment period during which participants were randomised to either continue on tirzepatide or switch to placebo
doi: 10.1016/j.ejogrb.2018.06.035 86 LinGZhongXLiSXuL
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The history of KPV is closely tied to the study of the alpha-melanocyte-stimulating hormone (-MSH), a peptide hormone known for its role in pigmentation, inflammation, and immune modulation
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