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Reduced appetite and rapid weight loss can sometimes lead to emotional side effects like irritability, emotional numbness, or anxiety

Unlike traditional weight loss medications that often target a single pathway, tirzepatide weight loss impacts both GLP-1 and GIP receptors, promoting a variety of metabolic benefits

This is because the body can meet L-arginine demands through dietary consumption of protein sources like fish and nuts, body protein breakdown, and endogenous L-arginine production by the kidneys

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the authors pointed out that this review was limited by the small number of eligible studies, as well as the differences in study designs and size, which made comparisons across studies difficult