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Why it matters: The GLP-1 market remains driven by weight loss efficacy
a BMI of 30 or higher with heart failure with preserved ejection fraction, uncontrolled high blood pressure, or moderate-to-advanced chronic kidney disease (stage 3a or higher)
Supports energy production, reduces fatigue, and is especially important for patients with malabsorption or colitis
Other reasons that could influence the improvement when switching from GLP1-AR could be different pharmacodynamic effects given the substantially varying biochemical properties and thereby a different effect on appetite, satiety, gastric emptying and insulin compared to the respective GLP-1 analogues (24)
|high blood pressure in the arteries of the lungs
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