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However, the exact mechanisms by which dual agonists enhance feeding suppression beyond GLP-1RAs remain unclear

The medication has a half-life of approximately seven days, which allows for once-weekly dosing and contributes to stable blood levels throughout the week

and the electron microscopy maps have been deposited in the Electron Microscopy Data Bank (EMDB) under accession codes: EMD-39621 (retatrutideGLP-1RG s complex), EMD-39622 (retatrutideGIPRG s complex) and EMD-39623 (retatrutideGCGRG s complex)

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