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In a human study published that same year, Khavinson and colleagues observed that elderly human subjects who received epithalamin treatment for two to three years experienced a 1.6-1.8 fold decreased mortality rate compared with a control group

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Fitness tracks with survival about as strongly as anything we can measure: in a study of over 120,000 people given an actual treadmill test, the least fit died at dramatically higher rates, and the steepest gains came at the bottom, from simply moving off the couch (Mandsager et al., 2018)

If the question is whether combining lipotropic formulations adds value or just duplicates cost, the answer depends entirely on whether your metabolic demand justifies addressing both bottlenecks