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The reason the gap matters is tolerability as much as efficacy
However, severe persistent vomiting (more than 3 episodes per day for more than 2 days), signs of pancreatitis (severe abdominal pain radiating to the back), or allergic reactions (hives, difficulty breathing, facial swelling) warrant immediate protocol cessation and medical attention
This suggests its potential in treatment
Med 89 , 457464 (2022)
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