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After numerous clinical trials by administration of the endogenous hormone to the body, the scientists found that though it appeared to work, -MSH had a very short half-life in the body to be practical as a therapeutic drug
L- 500-2000
Longer-term outcomes such as skin elasticity and joint symptoms showed improvements, while short-term measures like exercise recovery did not
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Most of these molecules are produced from oxygen in numerous metabolic processes occurring throughout the body, which primarily take place in the mitochondria, endoplasmic reticulum (ER) and peroxisomes
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