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The traditional treatment of vitamin B12 deficiency is the intramuscular injection of cyanocobalamin, generally 1 mg/day for one week, followed by 1 mg/week for one month, and then 1 mg every 1 or 2 months ad perpetuum [4, 18, 19]

Hepatology 15:11671172 Purucker E, Winograd R, Roeb E, Matern S (1998) Glutathione status in liver and plasma during development of biliary cirrhosis after bile duct ligation

Overall, both X(GD_L)f and X(GD) exhibit more stringent substrate requirements than wild-type BoNT/X protease or X(PC)

The liver is the main organ for vitamin B 12storage

In addition, it functions as an autocrine and paracrine agent, regulating the innate immune system, cell maturation, and differentiation (131133)